Association between cardiorespiratory fitness and mortality risk in the chilean population
e202503015
Keywords:
Cardiorespiratory Fitness, Mortality, Health Surveys, Adult, EpidemiologyAbstract
Background: The aim was to evaluate the relationship between equation-estimated cardiorespiratory fitness and all-cause mortality in the Chilean population of both genders according to data from the 2009-2010 National Health Survey (NHS).
Methods: Data from 4.749 participants from the 2009-2010 NHS were analysed after 10.9 years of follow-up. Fitness was estimated with the Myers et al. equation and classified into quintiles. All-cause mortality records were obtained from the Chilean Civil Registry and Identification until 2020. Cox regression models adjusted for confounding variables (demographics, nutritional status, lifestyle and comorbidities) were used to assess the association between fitness and mortality.
Results: During the 10.9 years (IQR: 10.8; 11.4) of follow-up 506 (10.6%) people died. Compared to the lowest fitness quintile (<7 METs) those classified in the highest quintile (>12 METs) had a 95% lower risk of mortality (HR: 0.05; 95% CI: 0.03, 0.09) and the risk of mortality was 28% lower for every 1-METs increase in fitness (HR: 0.72 95% CI: 0.69, 0.75). All these associations were independent of confounders.
Conclusions: Fitness has a strong association with all-cause mortality in the Chilean population, i.e. the reduction in risk of death varies between 28% and 95% with increasing and reaching a higher level of fitness, respectively.
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Copyright (c) 2025 Jaime Vásquez-Gómez, Yeny Concha-Cisternas , Solange Parra-Soto , Daniel Reyes-Molina , Felipe Díaz-Toro , Fanny Petermann-Rocha , Carlos Celis-Morales
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